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PTK PM Series Large Batch High Shear Mixer Granulator for Production

PTK PM Series Large Batch Production High Shear Mixer Granulator

PTK High Shear mixer granulators are designed for high-intensity batch mixing of pharmaceutical dry-powder blends and wet-granulated formulations. The PM Series batch mixer-granulator is ideally suited pharmaceutical manufacturing applications where blend content uniformity, uniform moisture dispersion and strict particle size control are required.

The PM Series mixer granulators are available with fixed mixing vessels with working capacities up to 840 liters. Ingredients may be loaded into the vessel by hand or by using the optional vacuum loading system. The binder can be introduced by an aperture located at the top of the mixing vessel, or can be introduced via an optional automatic binder dosing system. A sight glass and LED lamp in the lid allows the operator to view the mixing action. A bag filter is also mounted in the lid of the mixing vessel. The lid is counterweighted with a pneumatic cylinder to aid in opening the lid. The finished product is discharged via a sanitary valve located on the lower vessel wall.


Primary mixing action is achieved by a three blade main impeller, located at the bottom of the vessel. The main impeller has minimal clearance to the vessel bottom and walls to prevent product sticking.  A secondary horizontal chopper impeller de-agglomerates the mass, helps ensure uniform moisture and particle size distribution and aids in dispersing the powder and binding agents. Dry lubricants, liquids and binding agents can be added during processing. The mixing apparatus is easily disassembled for cleaning. 

The mixing vessel is mounted on a mobile base equipped with castors for mobility. The base, made type 304 stainless steel houses the impellor drives, electronics. The top of the base has with stainless steel safety railings and stairs to provide access to the mixing vessel and HMI podium.

The granulator utilizes PTK's advanced PIS-Con control system to monitor and control the mixing/granulating process via an HMI touch screen, which displays the granulation process in a user-friendly graphical format. The mixing end-point is determined by the control system by monitoring the impeller torque.

  • 316 SS construction with mirror finished product contact surfaces.
  • Mounted on castors for mobility
  • Type 304 stainless steel is used for exterior non-product contact surfaces
  • The “tulip” shape of the mixing vessel ensures increased mixing efficiency and better content uniformity of the final blend
  • The impellers are easily removed for cleaning
  • Machine operation is controlled by graphic-based HMI a touch screen
Model PM-1100 PM-1200 PM-1300 PM-1400 PM-1500 PM-1600
Vessel Volume Full Capacity (liters) 240 440 635 835 1,050 1,200
Working Capacity (liters) 74.4 - 173.6 132 - 308 190.5 - 444.5 249 - 581 315 - 735 360 - 840
Output Capacity (kg) * 37 - 87 66 - 154 95 - 222 125 - 291 158 - 368 180 - 420
Agitator Drive Motor (Kw) 11 15 22 30 37 45
Max Speed (RPM) 120 110 100 90 80 80
Chopper Drive Motor (Kw) 5.5 7.5 11 11 15 18.5
Max Speed (RPM) 3,400 3,400 3,400 3,400 3,400 3,400
Weight (kg) 1,950 2,500 2,600 2,750 3,000 3,500
Power Supply Data 220/380 VAC 3Ph 50/60Hz
Control Power 24 VDC

* At specific gravity of 0.5

The above specifications may be subject to change without notice.

  • Pis-Con PC-based control system with large color touch screen HMI with graphics, full process monitoring and control, end-point determination, data logging, recipe storage/ retrieval and meets 24 CFR Part 11 requirements. Mounted in separate brushed 304 SS cabinet with castors. 
  • Jacketed bowl for circulating a heating or cooling fluid. Does not include the apparatus for heating/cooling the fluid. (Which we can provide, if necessary)
  • Binding Solution Spray System for automatically adding binder liquids or slurries into the mixing vessel. Spray gun is mounted to the lid of the processing bowl with a sanitary quick connect fitting. Includes 316 stainless steel mirror-finish tank for holding the binder liquid which is mounted on top of the mobile cart housing the pump assembly.
  • Main Impeller Lift System for easy lifting and removal of the main impeller. Helps prevent operator injuries and damage to the impeller and the interior walls which can result from attempting to manually lift the large, unwieldy impeller during cleaning/maintenance.
  • Pneumatic Lid Opening System.
  • WIP System with spray nozzles located around the inside of the bowl. For repeatability, WIP can be programmed for automatic operation from the HMI if the PIS-Con enhanced control system upgrade is also purchased.
  • Additional Observation Port
  • Illuminated Observation Port
  • Illuminated Observation Port with Wiper
  • Stainless Steel Access Stairs with castors.
  • IQ/OQ Documentation
  • SAT Protocol Documentation
  • SAT Protocol Documentation
  • SAT Execution Assistance


Other options not listed here may be available. Please contact us to discuss your requirements in further detail.